Study of relation between hypertensive left ventricular hypertrophy and neurocrine factors

In this study of the relationship between hypertensive left ventricular hypertrophy (LVH) and neurohumor factors and ventricular arrhythmias, 180 cases were divided at random into 3 groups: 60 cases with primary hypertension and LVH (PH+LVH); 60 cases with simple hypertension (PH), and with other diseases and LVH(NPH+LVH). The results showed that 1. The excitability of the sympathetic nerve was not elevated while the activity of the vagus nerve was not significantly decreased in the patients with PH+LVH. The increased sympathetic nervous tension was correlated with the ventricular premature beat which was statistically correlated with the myocardial ischemia. 2. The patients’ condition in group PH+LVH was not correlated with the levels of aldosterone and insulin and was not even positively correlated with the levels of renin and angiotensin-II. 3. The patients in group PH+LVH had high incidence of ventricular premature beat and myocardial ischemia. 4. The patients’ condition in group NPH+LVH was not even positively correlated with the neurohumor factors but their heart failure was positively correlated, with the levels of aldosterone, sympathetic nervous tension, myocardial ischemia and ventricular premature beat.