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Analysis of censored data
Authors:Lucijanic Marko  Petrovecki Mladen
Affiliation:Division of Hematology, Department of Internal Medicine, Dubrava University Hospital, Zagreb, Croatia. markolucijanic@yahoo.com
Abstract:Analyzing events over time is often complicated by incomplete, or censored, observations. Special non-parametric statistical methods were developed to overcome difficulties in summarizing and comparing censored data. Life-table (actuarial) method and Kaplan-Meier method are described with an explanation of survival curves. For the didactic purpose authors prepared a workbook based on most widely used Kaplan-Meier method. It should help the reader understand how Kaplan-Meier method is conceptualized and how it can be used to obtain statistics and survival curves needed to completely describe a sample of patients. Log-rank test and hazard ratio are also discussed.
Keywords:actuarial method   censored data   Kaplan-Meier method   Log-rank test   survival analysis
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