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链霉菌次生代谢和形态分化调控研究进展
作者姓名:杨红文  程彦伟  张敬虎
作者单位:1. 漳州师范学院,福建,漳州,363000;华中农业大学农业微生物国家重点实验室,湖北,武汉,430070
2. 洛阳师范学院,河南,洛阳,471022
3. 漳州师范学院,福建,漳州,363000
摘    要:综述了链霉菌次生代谢、形态分化调控的研究近况,介绍了灰色链霉菌、天蓝色链霉菌、阿维链霉菌等几种常见链霉菌抗生素合成的途径专一性调控和全局性调控、菌丝分化和产孢等形态分化的调控等,包括A因子级联、BldA、双组分系统、sigma因子等参与的次生代谢和形态分化调控。

关 键 词:链霉菌  形态分化  次生代谢  双组分系统  sigma因子

Progess of Regulatory Mechanism of Morphological Differentiation and Secondary Metabolism in Streptomyces
Authors:YANG Hong-wen  CHENG Yan-wei  ZHANG Jing-hu
Institution:YANG Hong-wen CHENG Yan-wei ZHANG Jing-hu
Abstract:We review recent research about regulatory mechanism of secondary metabolism and morphological differentiation in S. griseus, S. coelicolor and S. avermitilis. The regulatory mechanism includes specific and comprehensive regulatory of antibiotic synthesis, regulatory of mycelium differentiation and spores formation as well, and the regulators includes A factor, BldA, Sigma factor and double component system.
Keywords:streptomyces  morphological differentiation  secondary metabolism  double component system  sigma factor
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