| GIF基因在小鼠中枢神经系统中的表达 |
| |
| 引用本文： | 余慧琳,康洁. GIF基因在小鼠中枢神经系统中的表达[J]. 商丘职业技术学院学报, 2006, 5(5): 95-97 |
| |
| 作者姓名： | 余慧琳 康洁 |
| |
| 作者单位： | 1. 商丘职业技术学院,河南,商丘,476000
2. 商丘师范学院生物系,河南,商丘,476000 |
| |
| 摘 要： | 本实验目的是探索G IF接种在脑内进行中枢神经系统疾病基因治疗的可行性.方法是用适量的G IF-GFP融合蛋白腺病毒载体直接注入c57小鼠脑内,3天、7天、28天、60天后分别用显微镜观察脑切片,结果发现G IF-GFP融合蛋白在脑中有表达且安全稳定.实验结果表明利用G IF进行中枢神经系统疾病的基因治疗是可行的.
|
| 关 键 词： | GIF 基因治疗 腺病毒载体 脑内接种 |
| 文章编号： | 1671-8127（2006）05-0095-03 |
| 收稿时间： | 2006-02-15 |
| 修稿时间： | 2006-02-15 |
Expression of GIF Gene in Little Mouse''''s Central Nervous System |
| |
| YU Hui-lin,KANG jie. Expression of GIF Gene in Little Mouse''''s Central Nervous System[J]. Journal of Shangqiu Vocational and Technical College Journal of Shangqiu Vocational and Technical College Journal of Shangqiu Vocational and Technical College, 2006, 5(5): 95-97 |
| |
| Authors: | YU Hui-lin KANG jie |
| |
| Abstract: | The aim of this experiment is to explore GIF inoculability's feasibility of gene treatment of nerve center system disease in the brain.The proper amount of GIF-GFP fusion protein adenovirus vector were directly injected into c57 mice's brain and the brain slices were made after 3 days,7 days,28 days and 60 days.As a result,we find that GIF:GFP fusion protein express itself safely and steadily in the brain.The result shows that it is feasible to cure the disease of nerve center system using GIF. |
| |
| Keywords: | gene treatment adenoviral vector inoculation in the brain |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
