| 低胆固醇林蛙卵油和植物甾醇(豆甾醇)在大鼠中的降脂作用（英文） |
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| 作者姓名： | Chang-hui ZHAO Chao ZHAO Hai-qing YE Chun-yu XI Zheng-ping ZOU Xin-hui ZHOU Ping-ping HOU Tie-hua ZHANG |
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| 作者单位： | College of Food Science and Engineering |
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| 基金项目： | Project supported by the Jilin Province Research and Industrialization with Key Technologies for High Value Processing and Safety Control of Agricultural Products(No.SF2017-6-4);the Jilin Provincial Department of Education(No.JJKH20180172KJ),China |
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| 摘 要： | 目的:探索林蛙副产物林蛙卵油的开发价值。创新点:首次验证了低胆固醇林蛙卵油的减重降脂功能。方法:Sprague-Dawley大鼠连续被灌胃8周后,分成8组:(1)对照组喂食标准饲料;(2)高脂组喂食60%高脂饲料;(3)阳性对照组喂食3.33 mg/(kg·d)辛伐他汀;(4)OORC组喂食2 g/(kg·d)的低胆固醇林蛙卵油(OORC);(5)植物甾醇组喂食0.48g/(kg·d)的豆甾醇;(6)低剂量组喂食1g/(kg·d)的低胆固醇OORC和0.24g/(kg·d)的豆甾醇;(7)中剂量组喂食2g/(kg·d)的低胆固醇OORC和0.48 g/(kg·d)的豆甾醇;(8)高剂量组喂食4 g/(kg·d)的低胆固醇OORC和0.96 g/(kg·d)的豆甾醇。经过不同方法处理后,比较各组大鼠的体重、器官指数,以及血清中总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白浓度。同时,对动物肝脏进行组织切片染色并评价损伤情况。结论:低胆固醇林蛙卵油或者其与植物甾醇(如豆甾醇)联用可以预防高脂饮食诱导的增重、肝损伤和高血脂症状。
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| 关 键 词： | 林蛙卵油 林蛙 肥胖 高血脂 |
Hypolipidemic activity of low-cholesterol ovum oil of Rana chensinensis and phytosterol(stigmasterol) in rats |
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| Chang-hui ZHAO,Chao ZHAO,Hai-qing YE,Chun-yu XI,Zheng-ping ZOU,Xin-hui ZHOU,Ping-ping HOU,Tie-hua ZHANG.Hypolipidemic activity of low-cholesterol ovum oil of Rana chensinensis and phytosterol(stigmasterol) in rats[J].Journal of Zhejiang University Science,2019(7):613-616. |
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