| 不同训练方式对大鼠腓肠肌p53和IL-6的影响 |
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| 引用本文： | 刘静霞,漆正堂,丁树哲. 不同训练方式对大鼠腓肠肌p53和IL-6的影响[J]. 北京体育大学学报, 2010, 0(2) |
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| 作者姓名： | 刘静霞 漆正堂 丁树哲 |
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| 作者单位： | 华东师范大学体育与健康学院; |
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| 基金项目： | 上海市浦江人才计划44038470;;教育部新世纪人才支持计划790013P8 |
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| 摘 要： | 目的:探讨不同训练方式对大鼠腓肠肌p53和IL-6的影响。方法:21只大鼠随机分为3组,即安静组(C,n=7),耐力训练组(E,n=7),间歇性冲刺训练组(S,n=7)。耐力训练组和间歇性冲刺训练组进行跑台训练8周;末次训练后24~48 h内,各组大鼠安静状态断颈处死,取腓肠肌。采用Elisa法分别测定腓肠肌中p53和IL-6水平。结果:1)E组(P<0.05)和S组(P<0.01)腓肠肌p53蛋白表达显著低于C组。2)E,S组腓肠肌IL-6表达与C组相比无显著性差异。结论:冲刺训练和耐力训练对P53的表达产生下调作用,在一定程度上可延缓骨骼肌衰老,同时间歇性运动效果更明显;而不同训练方式对IL-6的表达并未见有显著影响。
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| 关 键 词： | 运动 大鼠 P53 IL-6 训练方式 |
Effects of Different Exercise Modes on P53 and IL-6 Expression of Gastrocnemius Muscle in Rats |
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| LIU Jing-xia,QI Zheng-tang,DING Shu-zhe. Effects of Different Exercise Modes on P53 and IL-6 Expression of Gastrocnemius Muscle in Rats[J]. Journal of Beijing Sport University, 2010, 0(2) |
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| Authors: | LIU Jing-xia QI Zheng-tang DING Shu-zhe |
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| Affiliation: | College of Physical Education and Health;East China Normal University;Shanghai 200241;China |
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| Abstract: | Objective: To investigate the effects of different exercise modes on p53 and IL-6 in rats'gastrocnemius muscle.Methods:Twenty-one male SD rats arerandomly and equally divided into three groups: control group(C,n=7),endurance exercise group(E,n=7),and intermittent strenuous exercise group(S,n=7).The rats are sampled after 8-week exercise training.Between 24h and 48h after the last training,the rats are killed,gastrocnemius muscle are excised quickly for ELISA.Results: 1) The P53 expression of gastrocnemius m... |
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| Keywords: | exercise training rat P53 IL-6 exercise mode |
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