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Multilayered polyelectrolyte-coated gold nanorods as multifunctional optical contrast agents for cancer cell imaging |
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| Authors: | Li-li Chen Li Jiang Ya-lun Wang Jun Qian Sailing He |
| Affiliation: | 1. Centre for Optical and Electromagnetic Research, State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou, 310058, China 2. Department of Electromagnetic Engineering, School of Electrical Engineering, Royal Institute of Technology, S-100 44, Stockholm, Sweden |
| Abstract: | We report the application of multilayered polyelectrolyte-coated gold nanorods(GNRs) as multifunctional optical contrast agents for cancer cell imaging.The surface modification of GNRs improves their chemical stability and facilitates them to be taken up by cancer cells through electrostatic interaction.The unique longitudinal surface plasmon resonance property of GNRs makes them suitable as both scattering contrast agents and Raman contrast agents.In our experiments,the staining of GNRs in cells was furthe... |
| Keywords: | Gold nanorods Polyelectrolyte Scattering Raman Cancer cell imaging |
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