Erythrocyte aldehyde dehydrogenase activity in alcoholics and non-alcoholics and its value as a Biochemical marker in alcoholism |
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| Authors: | Govind Sharma R L Tripathi K S S Saibaba L M Srivastava |
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| Institution: | 1. Department of Biochemistry, All India Institute of Medical Sciences, 110 029, New Delhi, India
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| Abstract: | Erythrocyte aldehyde dehydrogenase (ALDH) activity in a normal reference population from North India was determined from results
of 22 healthy subjects (12 male and 10 female). We compared these data with results of 19 alcoholic patients (13 male and
6 female). The mean erythrocyte ALDH activity of male and female alcohol abusers was 16.2% and 20.9% lower than the mean values
for healthy subjects, respectively (P<0.001 and <0.01). It is proposed that erythrocyte ALDH activity may be a useful clinical
chemical marker of alcohol abuse and alcoholism. |
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