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High-stability spherical lanthanide nanoclusters for magnetic resonance imagingOA
作者姓名:Hai-Ling Wang  Donglin Liu  Jian-Hua Jia  Jun-Liang Liu  Ze-Yu Ruan  Wei Deng  Shiping Yang  Si-Guo Wu  Ming-Liang Tong
作者单位:1. Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education, School of Chemistry, Sun Yat-sen University;2. College of Chemistry and Materials Science, Shanghai Normal University
基金项目:supported by the National Key Research and Development Program of China (2018YFA0306001);;the National Natural Science Foundation of China (22131011, 91959105and 21821003);
摘    要:High-nuclear lanthanide clusters have shown great potential for the administration of high-dose mononuclear gadolinium chelates in magnetic resonance imaging(MRI). The development of high-nuclear lanthanide clusters with excellent solubility and high stability in water or solution has been challenging and is very important for expanding the performance of MRI. We used N-methylbenzimidazole-2-methanol(HL) and LnCl3·6H2O to synthesize two spherical lanthanide clusters, Ln

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