2，6-二叔丁基-4（二甲氨甲基）苯酚的合成

以2，6-二叔丁基苯酚，甲醛，二甲胺为原料，通过mannich反应合成了抗氧剂2，6-二叔丁基-4（二甲氨甲基）苯酚，并采用红外光谱和质谱对其结构进行了表征．通过正交实验确定了抗氧剂2，6-二叔丁基-4（二甲氨甲基）苯酚的最佳合成工艺：第一步反应温度为5℃，反应时间为40min；第二步反应温度为80℃，反应时间为3．5h；2，6-二叔丁基苯酚与甲醛和二甲胺的物质的量的比分别为1：1．7，1：2．7．产品的收率为94．7％，熔点为91-92℃．

Synthesis of 2,6-di-tert-butyl-4(dimethyl amino methyl) phenol

By use of Mannich reaction, the antioxidizer2,6-di-tert-butyl-4（dimethyl amino methyl） phenol was synthesized with 2,6 di-tert-butyl phenol, formaldehyde and dimethylamine as the raw materials. The characterization of the structure of 2,6-di-tert-butyl-4 （dimethyl amino methyl） phenol was done by means of IR and mass spectrometry. And the optimal synthesis technologywas determined by means of orthogonal experiment： The reaction temperature of the first step was 5℃ with the reaction time being 40min; the reaction temperature in the second step was 80℃ with the reaction time of 3.5h; molar ratio of 2,6 - di-tert-butyl phenol to formaldehyde and to dimethylamine were 1 ： 1.7, 1 ： 2.7 respeactively. Under these optimum reaction conditions,the yield of 2,6-di-tert-butyl-4（dimethyl amino methyl） phenol was 94.7 % and the melting point was 91-92℃.