Abstract: | This paper presents a case study for use in the teaching of bioprocess design. Taking the production and isolation of an intracellular protein from S. cerevisae , it demonstrates how undergraduates can use a range of data to construct and then to investigate the range of process flowsheet options available for such a process duty. The paper considers the role of newer operations, such as expanded bed technology, alongside more traditional process routes. An integrated view of bioprocess design is developed to demonstrate how unit operations interact and hence enable students to determine the eventual overall process performance that is achieved. |