| 竹红菌甲素对人黑色素瘤B-16细胞的杀伤效应 |
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| 引用本文： | 张俭,伍贤进,马岚.竹红菌甲素对人黑色素瘤B-16细胞的杀伤效应[J].黔南民族师范学院学报,2004,24(6):35-36,86. |
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| 作者姓名： | 张俭 伍贤进 马岚 |
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| 作者单位： | 1. 怀化学院,生物系,湖南,怀化,418008
2. 云南大学,生命科学学院,云南,昆明,650091 |
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| 基金项目： | 湖南省怀化学院2003科研基金项目． |
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| 摘 要： | 从生物学角度上对竹红菌甲素(HA)光敏活性进行了研究，运用MTT法实验发现HA合并光照处理人黑色素瘤B-t6细胞，HA对B-16细胞具有明显的杀伤作用，使癌细胞存活率显著下降，结果表明HA具有光敏抗癌活性。
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| 关 键 词： | 竹红菌甲素 光敏损伤 MTT法 |
| 文章编号： | 1005-6769(2004)06-0035-02 |
Hypocrellin A-Sensitized Photodamage on Human Melanoma B-16 Cell |
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| ZHANG Jian,WU Xian-jin,MA Lan.Biology.Hypocrellin A-Sensitized Photodamage on Human Melanoma B-16 Cell[J].Journal of Qiannan Normal College of Nationalities,2004,24(6):35-36,86. |
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| Authors: | ZHANG Jian WU Xian-jin MA LanBiology |
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| Institution: | ZHANG Jian~1 WU Xian-jin~1 MA Lan~21.Biology Department,Huaihua University,Huaihua 418008,China,2.College of Life Science,Yunnan University,Kunming 650091,China |
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| Abstract: | The photosensitive bioactivity of Hypocrellin A(HA)was mainly investigated.The microculture tetrazolium assay was used to evalu-ate the inhibitive effect of HA on the proliferation of human melanoma B-16 cell.The experiment indicated that the survival rate of these cancercells decreased obviously following the irradiation in presence of HA.And the results showed that HA had photosensitive anti-cancer activity. |
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| Keywords: | hypocrellin A photodamage the microculture tetrazolium assay |
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