Glycoprotein components in the serum of patients with cancer breast |
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Authors: | Miriam Varkey R Sundara Devi Shrinivas B Rao |
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Institution: | (1) Departments of Biochemistry, Medical College, 695 011 Thiruvananthapuram;(2) Kasturba Medical College, 575 001 Mangalore |
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Abstract: | The levels of total sialic acid, lipid bound sialic acid and fucose were estimated in the sera of patients with benign and
malignant tumours of breast. An increase was noted in all the three parameters, with a more marked increase in malignancy,
when compared with benign and controls. Consequent to surgery, there was an elevation in the serum levels of the above parameters
than the values prior to surgery and a decline was noted two months after surgery although none of the values reached the
normal range. These results suggest a close association of the glycoproteins with the tumour burden and further signify their
role in early detection and staging of cancer breast. |
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Keywords: | Cancer breast Benign breast disease Total sialic acid Lipid bound sialic acid Fucose Biomarkers |
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