同种异体肾移植26例报告

目的 总结26例肾移植的临床经验和教训。方法 回顾26例肾移植的临床资料，分析供受的状况，组织配型，移植手术，术后并发症及免疫抑制治疗方案对移植效果的影响。结果 70年代有80年代一年人／肾存活率均为33．3％／33．3％，90年代一年，三年人／肾存活率分别为90％／85％，80％／75％，超急性排斥反应发生率3．9％，急性及慢性排斥反应发生率均为11．5％，药物中毒发生率7．8％。结论 合理应用免疫抑制剂，提高外科手术，加强组织配型是提高肾移植受存活率的关键因素。

A Retrospective Study on 26 Cases of Allogenic Kidney Transplantaion

Objective To evaluate the clinical application of kidney transplantation to improve transplant effect. Methods The data of kidney transplantation in 26 cases was summarized. All the factors related to transplant effect were analyzed, such as conditions of donor and recipient, tissure matching, surgical procedure, complications and immunosuppressants. Results The 1 year survival rate(%)of recipient/kidney was 33. 3 % /33.3 % in early stage, the 1 or 3 years survival rate of recipient/kidney was 90 % /85 %, 80 % /75 % recently;The incidence of hyperacuterejection, acute rejection and chronic rejection was 3.9%, 11. 5% and 11.5% respectively. 2 cases had drug toxicity. Conclusion The reasonable using of immunosuppressants, improving surgical techniques and the ideal tissue matching are all the important factors for the success of kidney transplantation.