| 内皮型一氧化氮合酶基因多态性与原发性高血压关系的研究进展 |
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| 引用本文： | 韩清泉.内皮型一氧化氮合酶基因多态性与原发性高血压关系的研究进展[J].搏击·武术科学,2012(10):122-124. |
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| 作者姓名： | 韩清泉 |
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| 作者单位： | 苏州大学体育学院, 江苏 苏州 215006 |
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| 摘 要： | 内皮型一氧化氮合酶(eNOS)是一氧化氮(NO)合成的限速酶,NO 是外周与中枢神经系统的神经递质,在心血管系统具有维持血管张力,调节血压等功能.一旦 eNOS 突变,NO 生成不足,即可引起高血压.文章对 eNOS 基因 G894T、T786C 和27 bpVNTR 的多态性与原发性高血压关系的研究进展作一综述.
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| 关 键 词： | 原发性高血压 一氧化氮合酶 基因多态性 |
The Research Progress of the Relationship between Gene Polymorphoism of eNOS and Essential Hypertension |
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| Han Qingquan.The Research Progress of the Relationship between Gene Polymorphoism of eNOS and Essential Hypertension[J].BOJI(WUSHUKEXUE),2012(10):122-124. |
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| Authors: | Han Qingquan |
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| Institution: | Han Qingquan(P.E.School of Soochow University,Suzhou Jiangsu 215006,China) |
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| Abstract: | Endothelial nitricoxide synthase(eNOS) is a rate-limiting enzyme of the synthesizing of NO.NO is the neurotransmitter between peripheral nerve and central nerve system with the ability of maintaining the tension of blood vessels and regulateing blood pressure.The mutation of eNOS will result in less synthesizing of NO which can rouse hypertension.This article makes the summarization of research progress of the relationship between the polymorphism of three kinds of eNOS gene and the essential hypertension. |
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| Keywords: | Essential Hypertension Endothelial nitric oxide synthase Gene polymorphoism |
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