| 肺炎衣原体与急性心梗、心绞痛型冠心病的关系 |
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| 引用本文： | 李文化,张雪雨,刘锐峰,程铮,李新军,宋彦恩. 肺炎衣原体与急性心梗、心绞痛型冠心病的关系[J]. 河北北方学院学报(医学版), 2007, 24(4): 11-13 |
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| 作者姓名： | 李文化 张雪雨 刘锐峰 程铮 李新军 宋彦恩 |
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| 作者单位： | 河北北方学院附属第二医院内四病区,河北,宣化,075100 |
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| 基金项目： | 河北省科学技术研究与发展计划 |
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| 摘 要： | 目的：探讨肺炎衣原体（TWAR）与急性心梗（AMI）、心绞痛（Angina）型冠心病之间的关系。方法：采用多聚合酶链反应（PCR）技术对200例冠心病（急性心梗56例,不稳定心绞痛124例,稳定心绞痛20例）和180例非冠心病患者进行全血标本肺炎衣原体DNA检测。结果：急性心梗组肺炎衣原体DNA阳性率为73.2%,不稳定心绞痛组为52.4%,稳定心绞痛组为45.0%;对照组为21.1%,三组与对照组相比,差异均有显著性（P〈0.01,P〈0.01,P〈0.05）。结论：肺炎衣原体感染与急性心梗、心绞痛型冠心病存在密切关系。
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| 关 键 词： | 肺炎衣原体 急性心梗 心绞痛 多聚酶链反应 核酸 |
| 文章编号： | 1673-1484（2007）04-0011-03 |
Investigating the Relationship between Chlamydia Pneumoniae and Acute Myocardio Infarction or Angina in CHD Patients |
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| LI Wen-hua, ZH ANG Xue-yu, LIU Rui-feng, et al. Investigating the Relationship between Chlamydia Pneumoniae and Acute Myocardio Infarction or Angina in CHD Patients[J]. Journal of Hebei North University:Medical Edition, 2007, 24(4): 11-13 |
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| Authors: | LI Wen-hua ZH ANG Xue-yu LIU Rui-feng et al |
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| Affiliation: | Internal Medicine Department,The Second Affiliated Hospital, Hebei North Univercity,Xuanhua,075100,Hebei,China |
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| Abstract: | Objective: To investigate the relationship between chlamydia pneumoniae(TWAR) and coronary heart disease(CHD) with acute myocardio infarction or angina.Methods: By means of polymerase chain reaction(PCR),TWAR nucleic acid was detected in 56 patients with acute myocardio infarction,124 patients with unstable angina,stable angina;and 180 control subjects.Results: The positive rates of TWAR-DNA were 73.2%,52.4%,45.0% in the AMI,unstable angina,stable angina patients and 21.1% in the control group respectively;which showed significant difference(P<0.01,P<0.01,P<0.05).Conclusion: TWAR infection is closely connected with CHD(acute myocardio infarction or angina),and may be one of the risk factors in CHD mechanisms. |
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| Keywords: | Chlamydia pneumoniae Acute myocardio infarctions Angina Polymerase chain reactions Nucleic acid |
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