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豫北地区猪源致病性大肠杆菌油乳剂灭活疫苗的研制
引用本文:李培庆,赵坤,杨志华,常天星.豫北地区猪源致病性大肠杆菌油乳剂灭活疫苗的研制[J].河南科技学院学报,2007,35(4):24-26.
作者姓名:李培庆  赵坤  杨志华  常天星
作者单位:[1]河南科技学院,河南新乡453003 [2]辉县市拍石头乡政府,河南辉县453600
基金项目:河南省自然科学基金项目(0611030800)
摘    要:用从河南省豫北地区大型种猪场发病猪群分离到的致仔猪黄痢、白痢6个大肠埃希氏菌优势血清型菌株O2,O139,O101,O138,O20,O60的两次培养物,经0.4%的福尔马林灭活48h,添加油乳佐剂充分乳化,制成地方性猪大肠埃希氏菌灭活苗,含菌量为150亿/mL.分别于产前30d和14d两次免疫妊娠母猪,剂量2mL头,使初生仔猪从母乳中获得较高含量的大肠埃希氏菌抗体,具有对抗黄痢、白痢发生的免疫力。

关 键 词:  大肠埃希氏菌  仔猪黄、白痢  灭活苗
文章编号:1673-6060(2007)04-0024-03
收稿时间:2007-05-19

Development of Inactivated Oil-Emulsion Vaccenes of the North of Henan Source Vaccine of Escherichia Coli for Piglets
LI Pei - qing ,et al.Development of Inactivated Oil-Emulsion Vaccenes of the North of Henan Source Vaccine of Escherichia Coli for Piglets[J].Journal of Henan Institute of Science and Technology(Natural Science Edition),2007,35(4):24-26.
Authors:LI Pei - qing  
Abstract:Cultures of 6 superior main of E. eoli to cause yellow scour and white scour of piglets, isolated from pig farms for reproduction of the north of Henan, were made of inactivated vaccine by 0.4% ,than appese oil emulsion adjuvants and adequate emulsify eomentration of formaldehyde. It contained 15 billion germs per ml. The inactivated vaccine was safe and was a good immunogenicity.
Keywords:piglets  Eseheriehia eoli  yellow scour and white scour of piglets  inactivated vaccine
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