| 肿瘤出芽与直肠腺癌的临床病理学关系分析 |
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| 引用本文： | 陈军芳,许三林,陈争春,黄勇进. 肿瘤出芽与直肠腺癌的临床病理学关系分析[J]. 孝感职业技术学院学报, 2014, 0(3): 105-108 |
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| 作者姓名： | 陈军芳 许三林 陈争春 黄勇进 |
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| 作者单位： | 1. 湖北职业技术学院 医学院,湖北 孝感,432000
2. 湖北航天医院病理科,湖北 孝感,432000 |
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| 基金项目： | 湖北职业技术学院重点资助项目“肿瘤出芽在消化管癌病理诊断中的意义”(项目编号2012 A05)的阶段性研究成果之一。 |
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| 摘 要： | 观察发现，209例直肠腺癌中有112例发生了肿瘤出芽，出芽率为53；．59％。肿瘤出芽的发生率与直肠腺癌的淋巴结转移、淋巴管侵润、血管侵润、神经侵润和TNM分期明显相关（ P＜0．01），与肿瘤的浸润深度也有关（P＜0．05），但与肿瘤的分化程度无关（P＞0．05）。这表明肿瘤出芽是提示直肠腺癌侵袭性生长的形态学特征，有肿瘤出芽现象提示患者可能预后较差。
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| 关 键 词： | 直肠腺癌 肿瘤出芽 病理学 |
Analysis on the Relationship of Clinical Pathology Between Tumor Budding and Rectum Adenocarcinom |
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| CHEN Jun-fang,XU San-lin,CHEN Zheng-chun,HUANG Yong-jin. Analysis on the Relationship of Clinical Pathology Between Tumor Budding and Rectum Adenocarcinom[J]. Journal of Xiaogan Vocational-Technical College, 2014, 0(3): 105-108 |
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| Authors: | CHEN Jun-fang XU San-lin CHEN Zheng-chun HUANG Yong-jin |
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| Affiliation: | CHEN Jun-fang, XU San-lin, CHEN Zheng-chun, HUANG Yong-jin (1. School of Medicine, Hubei Polytechnic Institute, Xiaogan, Hubei 432000, China; 2. Department of Pathology, Hubei Space Hospital, Xiaogan, Hubei 432000, China) |
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| Abstract: | Objective ： To study the clinical pathologic significance of tumor budding in rectum adenocarcinoma. Methods： The tumor budding of 209 cases of rectum adenocarcinoma were detected by HE staining. Results： Tumor budding were found in 112 cases of rectum adenocarcinoma（53.59% ）. The incident of tumor budding in rectum adenocarcinoma had a significant correlation （P 〈 0.01 ） with lymph node metastasis, lymphatic invasion, vascular invasion, nerve invasion, and TNM stages. Also it had a correlation with tumor infiltration depth （P 〈 0. 05 ）. But it didnt relate to its differentiation （P 〉 0.05 ）. Conclusion： Tumor budding was a potential pathological marker suggesting aggressive of rectum adenocarcinoma and it will have a poor prognosis for patients with tumor budding. |
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| Keywords: | rectum adenocarcinoma tumor budding pathology |
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