TMAs技术及其在体育生物科学领域中的应用展望

研究目的:探讨组织微阵列(tissuemicroarrays,TMAs或tissuechip)技术在体育生物科学领域中的应用前景。研究方法:采用历史回顾与前瞻性分析及逻辑推理相结合的方法,跟踪TMAs技术的发展及其在体育生物科学领域中的应用。研究结果与结论:TMAs技术是近年来基因芯片(DNA芯片)为代表的生物芯片技术的发展和延伸,它与细胞芯片、蛋白质芯片、抗体芯片一样,属于一种特殊的生物芯片技术。它将成百上千个不同个体或/和同一个体不同器官的组织标本排列在一张载玻片上所形成的组织微阵列生物芯片。TMAs是一种高通量、并行性、多样本研究mRNA、DNA、基因以及蛋白质定位、定性和相对定量的分析工具,在体育生物科学领域中具有广阔的应用前景。

TMAs Technology and Its Application Prospect in Sports Biological Sciences

Objective: To study and research the application prospect of tissue microarrays (TMAs) Technology in Sports Biological Sciences. Method: By the means of history review and logic inference, we summarized the development of TMAs technology and its application in sports biology. Results and Conclusion: TMAs technology is the development and extension of bio-chip technology represented by the gene chip (DNA chip) in recent years. It is a kind of special biochip technology as well as cell chip, protein chip and antibody chip, which arrange thousands of samples of different bodies or/and organs of the same body on a glass slider. TMAs is a kind of high through, parallel, multi-samples analysis tools applied in studying mRNA, DNA, and protein location, which has a wide foreground in sports biology. TMAs technique will help to accelerate the transition from basic research to clinical application in sports biology.