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Insulin sensitivity derived from oral glucose tolerance testing in athletes: Disagreement between available indices
Authors:Konstantinos Niakaris  Faidon Magkos  Nikos Geladas  Labros S Sidossis
Affiliation:1. Department of Sport Medicine and Biology of Exercise, Faculty of Physical Education and Sport Sciences , University of Athens , Athens and;2. Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics , Harokopio University , Athens, Greece
Abstract:The aims of the present study were to determine whether available “fasting” and oral glucose tolerance test-derived insulin sensitivity indices could effectively discriminate between individuals with higher than normal insulin sensitivity, and whether they would all provide similar information in clinical practice. Sprint runners (n = 8), endurance runners (n = 8) and sedentary controls (n = 7) received a 75-g oral glucose tolerance test. All participants were healthy lean males, aged 21?–?29 years. Besides glucose and insulin responses, a total of nine such indices were computed. Fasting as well as post-load glucose concentrations were similar in the three groups, while basal plasma insulin and the insulinaemic response to glucose were both higher in untrained individuals (at P?P?P?
Keywords:Athletes  endurance  glucose tolerance  insulin sensitivity  oral glucose tolerance test  sprint
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