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川芎茶调冲剂的解热镇痛作用
引用本文:许实波,赵桂玲,邱光清,项辉,张伟强,梁燕茹.川芎茶调冲剂的解热镇痛作用[J].中山大学学报论丛,1994(6).
作者姓名:许实波  赵桂玲  邱光清  项辉  张伟强  梁燕茹
作者单位:中山大学生命科学学院药理室 (许实波,赵桂玲,邱光清,项辉),广东省佛山制药二厂 (张伟强),广东省佛山制药二厂(梁燕茹)
摘    要:川芎茶调剂给小鼠灌胃的最大耐受量为44.76g/kg,按最大耐受量的1/12,1/24,1/48设置川芎茶高、中、低3个剂量灌胃给药,川芎茶使大鼠炎症足和非炎症足的痛阈均显著上升,能提高大鼠鼠尾电刺激的痛阈值,对电刺激家免齿髓致痛也有显著抑制作用,结果表明川芎茶调剂具显著的解热镇痛作用.

关 键 词:川芎茶调剂  解热  镇痛

Study on Analgesic Effect and Abatement of Fever of Chuanxiong Tea
Xiu Shibo Zhao Guiling Qiu Guangqing Xiang Hui Zhang Weiqiang Liang Yanru Section of Pharmacology,School of Life Sciences,Zhongshan University.Study on Analgesic Effect and Abatement of Fever of Chuanxiong Tea[J].Supplement to the Journal of Sun Yatsen University,1994(6).
Authors:Xiu Shibo Zhao Guiling Qiu Guangqing Xiang Hui Zhang Weiqiang Liang Yanru Section of Pharmacology  School of Life Sciences  Zhongshan University
Abstract:Maximum tolerance dose (MTD) of Chuangxiong Tea P. O in mice was 44. 76 g/kg. 3 doses according to 1/12, 1/24,1/48 of MTD were set up. Chuanxiong tea inhibited the pains of rat paw, rat cauda and rabbit dental medulla evoked by electrical stimulus; and abatement of fever in rabbit by baker's yeast. These results show that Chuanxiong tea has obvious analgesic effect and abatement of fever, it's, machnism could be on centrel nervous system.
Keywords:Chuanxiong tea  analgesa  abatement of fever
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