| 绞股蓝皂甙和大豆皂甙对神经干细胞分化的影响 |
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| 引用本文： | 吴婕,文铁桥.绞股蓝皂甙和大豆皂甙对神经干细胞分化的影响[J].上海大学学报(英文版),2008,12(1):91-94. |
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| 作者姓名： | 吴婕 文铁桥 |
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| 作者单位： | Laboratory of Neural Molecular Biology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China |
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| 基金项目： | 国家重点基础研究发展计划(973计划)
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国家自然科学基金
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上海市科委资助项目 |
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| 摘 要： | Neural stem cell has a potential to differentiate into neurons, astrocytes and oligodendrocytes. It provides an in vitro model to screen herbal medicines on the cellular differentiation and development level. In this work, active component from gypenosides and soyasaponins was prepared to investigate their effects on the differentiation of neural stem cells.. Both gypenosides and soyasaponins promote the differentiation of neural stem cells. This method provides speed and practicality for screening effective herbal medicine. It is well suited for studying the mechanism of cell differentiation and development.
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| 关 键 词： | 绞股蓝皂甙 大豆皂甙 神经干细胞 细胞分化 |
| 文章编号： | 10.1007/s11741-008-0118-1 |
| 收稿时间： | 2006-07-07 |
| 修稿时间： | 2006-09-25 |
Evaluating effects of gypenosides and soyasaponins on differentiation of neural stem cells as an in vitro model |
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| WU Jie,WEN Tie-qiao.Evaluating effects of gypenosides and soyasaponins on differentiation of neural stem cells as an in vitro model[J].Journal of Shanghai University(English Edition),2008,12(1):91-94. |
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| Authors: | WU Jie WEN Tie-qiao |
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| Institution: | Laboratory of Neural Molecular Biology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China |
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| Abstract: | Neural stem cell has a potential to differentiate into neurons, astrocytes and oligodendrocytes. It provides an invitro model to screen herbal medicines on the cellular differentiation and development level. In this work, active componentfrom gypenosides and soyasaponins was prepared to investigate their effects on the differentiation of neural stem cells.. Bothgypenosides and soyasaponins promote the differentiation of neural stem cells. This method provides speed and practicalityfor screening effective herbal medicine. It is well suited for studying the mechanism of cell differentiation and development. |
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| Keywords: | neural stem cell gypenosides soyasaponins herbal medicine in vitro model |
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