A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway |
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| Authors: | Email author" target="_blank">Lin?Xin-daEmail author Lin?Xin-hua Cheng?Jia-an |
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| Institution: | (1) Institute of Applied Entomology, Zhejiang University, 310029 Hangzhou, China;(2) Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, 45229 Cincinnati, OH, USA |
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| Abstract: | A wing specific F 1 genetic screen was carried out using the powerful Drosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped. |
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| Keywords: | Drosophila Genetic screen Wingless signal transduction Mutant allele |
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