| 耳蜗外毛细胞Prestin的研究进展 |
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| 引用本文： | 张斌,王杨科,李丽霞.耳蜗外毛细胞Prestin的研究进展[J].陕西理工学院学报(社会科学版),2003,21(6):84-88. |
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| 作者姓名： | 张斌 王杨科 李丽霞 |
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| 作者单位： | 1. 华东师范大学,生命科学院,上海,200062
2. 陕西理工学院,生物系,陕西,汉中,723000 |
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| 摘 要： | 哺乳动物耳蜗外毛细胞能响应膜电位变化，其长度和劲度(stiffness)均能发生迅速改变．外毛细胞的这种电动性被认为是由分子马达(motor)驱动，能产生耳蜗机械放大。Prestin特异地在外毛细胞内表达，近年的研究认为Prestin正是耳蜗外毛细胞的分子马达，对近年来有关Prestin的结构功能特性的研究结果进行了较详细论述。
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| 关 键 词： | Prestin 外毛细胞 电动性 |
| 文章编号： | 1007-0842(2003)06-0084-05 |
| 修稿时间： | 2003年1月10日 |
The Progress of Studies on Prestin Protein of Cochlear Outer Hair Cells |
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| ZHANG Bin,WANG Yang-ke,LI Li-xia.The Progress of Studies on Prestin Protein of Cochlear Outer Hair Cells[J].Journal of Shaanxi University of Technology:Social Sciences,2003,21(6):84-88. |
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| Authors: | ZHANG Bin WANG Yang-ke LI Li-xia |
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| Institution: | ZHANG Bin~1,WANG Yang-ke~2,LI Li-xia~2 |
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| Abstract: | The outer hair cells of the mammalian cochlea can rapidly alters its length and stiffness. In response to changes in membrane potential. This electromotility assumed to be driven by molecular motors produce amplification of vibrations in the cochlea, Prestin, which is specifically expressed in outer hair cells, recently has been identified and proposed as this molecular motor. in this article, we particularly introduced the structural and functional characteristics of prestin studied in recent years. |
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| Keywords: | Prestin outer hair cells electromotility |
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