| 长期运动训练对老年小鼠心肌线粒体功能的影响 |
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| 引用本文： | 陈彩珍,卢健,许豪文,许永刚,赖荣兴,黄丽英.长期运动训练对老年小鼠心肌线粒体功能的影响[J].武汉体育学院学报,1999(5). |
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| 作者姓名： | 陈彩珍 卢健 许豪文 许永刚 赖荣兴 黄丽英 |
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| 作者单位： | 广州体育学院(陈彩珍，卢健，许永刚，赖荣兴，黄丽英)，华东师范大学(许豪文) |
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| 基金项目： | 1997 年度广东省高教厅自然科学基金 |
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| 摘 要： | 以Ｃ５７ＢＬ／６Ｊ雄性小鼠跑转笼为运动方式，研究了从５ 月龄开始进行为期８个月的运动训练对小鼠心肌线粒体复合物Ｉ、复合物ＩＶ及ＡＤＰ／Ｏ比值的影响。发现复合物ＩＮＶＤＨ脱氢酶活性及ＡＤＰ／Ｏ比值随增龄而降低，ＭＤＡ含量随增龄而升高；而运动训练使心肌线粒体呼吸链出现显著的适应性变化，从而减弱衰老过程中自由基产生增多造成的损伤
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| 关 键 词： | 长期运动训练 心肌 线粒体呼吸链 MDA |
Effects of Long Term Physical Training on the Mitochondrial Function in Mice Heart |
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| Chen Caizhen,Lu Jian,Xu Haowen,et al.Effects of Long Term Physical Training on the Mitochondrial Function in Mice Heart[J].Journal of Wuhan Institute of Physical Education,1999(5). |
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| Authors: | Chen Caizhen Lu Jian Xu Haowen |
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| Abstract: | The effects of long term physical training on the age related changes of mitochondrial repiratory chain function in mice heart were investigated.The result indicates that the activities of complex I and complex IV were decreased in the aging process,and MDA contents were increased.The adaptation changes of mitochondrial repiratory chain appeared after prolonged physical training,which inhibited lipid peroxidant in aging mice heart. |
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| Keywords: | Physical training Mitochondrial repiratory chain Lipid peroxidant |
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