| 海洋放线菌抗肿瘤活性物质研究进展 |
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| 引用本文： | 赵俊凌,古静燕,侯大斌.海洋放线菌抗肿瘤活性物质研究进展[J].绵阳师范学院学报,2007,26(2):91-94. |
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| 作者姓名： | 赵俊凌 古静燕 侯大斌 |
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| 作者单位： | 1. 西南科技大学生命学院,四川绵阳,621010
2. 绵阳师范学院分子生物学与生物制药重点实验室,四川绵阳,621000 |
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| 基金项目： | 绵阳市应用与开发技术项目 |
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| 摘 要： | 与陆生放线菌相比,海洋放线菌已经进化出了独特的代谢途径,它们的次级代谢产物显示出化学结构多样性、复杂性以及更强的生物活性,这些活性物质为新药研究、开发,特别是抗肿瘤药物开发提供丰富的先导化合物。本文对海洋放线菌抗肿瘤活性物质的研究进展进行了概述。
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| 关 键 词： | 海洋放线菌 生物活性 抗肿瘤 |
| 文章编号： | 24313512 |
| 修稿时间： | 11 26 2006 12:00AM |
Progress in the Research of Active Antineoplastic Substance Derived from Marine Actinomycetes |
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| ZHAO Jun-ling,GU Jing-yan,HOU Da-bin.Progress in the Research of Active Antineoplastic Substance Derived from Marine Actinomycetes[J].Journal of Mianyang Normal University,2007,26(2):91-94. |
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| Authors: | ZHAO Jun-ling GU Jing-yan HOU Da-bin |
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| Institution: | 1. College of Life Science, Southwest University of Science and Technology, Mianyang, Sichuan 621010; 2. Key Laboratory of Molecular Biology and Biopharmaceuticals,Mianyang Normal University, Mianyang, Sichuan 621030 |
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| Abstract: | Compared with that of terrestrial actinomycetes,marine-derived actinomycete has evolved the peculiar metabolism approach.The secondary metabolites produced by marine actinomycetes display wide diversity and distinct complexity in chemical structures,as well as the predominant biological activity.Therefore,these bioactive substances can provide the abundant lead-compounds for new drugs' research,especially the antineoplastic drug. This article summarizes briefly the progress in the research of antineoplastic substance from marine actinomycete. |
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| Keywords: | marine actinomycete biological activity antitumor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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