Molecular biomarkers of colorectal cancer: prognostic and predictive tools for clinical practice |
| |
Authors: | Wei-qin Jiang Fang-fang Fu Yang-xia Li Wei-bin Wang Hao-hao Wang Hai-ping Jiang Li-song Teng |
| |
Institution: | 1Cancer Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China;2Institute of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China |
| |
Abstract: | Colorectal cancer remains one of the most common types of cancer and leading causes of cancer death worldwide. Although we have made steady progress in chemotherapy and targeted therapy, evidence suggests that the majority of patients undergoing drug therapy experience severe, debilitating, and even lethal adverse drug events which considerably outweigh the benefits. The identification of suitable biomarkers will allow clinicians to deliver the most appropriate drugs to specific patients and spare them ineffective and expensive treatments. Prognostic and predictive biomarkers have been the subjects of many published papers, but few have been widely incorporated into clinical practice. Here, we want to review recent biomarker data related to colorectal cancer, which may have been ready for clinical use. |
| |
Keywords: | Colorectal cancer Biomarker Predictive value Prognostic value Chemotherapy Targeted therapy |
本文献已被 CNKI SpringerLink 等数据库收录! |
|