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Inhibitory effect of Jeju endemic seaweeds on the production of pro-inflammatory mediators in mouse macrophage cell line RAW 264.7
Authors:Eun-Jin Yang  Ji-Young Moon  Min-Jin Kim  Dong Sam Kim  Chan-Shick Kim  Wook Jae Lee  Nam Ho Lee and Chang-Gu Hyun
Institution:(1) Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153, Japan;(2) Department of Life Science, Bar-Ilan University, Ramat-Gan, 52900, Israel;(3) Faculty of Engineering, The Science University of Tokyo, 1-3, Kagurazaka, Shinjuku-ku, Tokyo, 162, Japan;(4) Toyo Susan Kaisha Ltd, 2-13-40 Kohnan, Minato-ku, 108 Tokyo, Japan;(5) Faculty of Information Science, Hiroshima City University, 151-5, Ozuka, Numata-cho, Asaminami-ku, Hiroshima, 731-31, Japan;(6) Japanese Red Cross College of Nursing, 4-1-3, Hiro-o, Shibuya-ku, Tokyo, 150, Japan
Abstract:Seaweed has been used in traditional cosmetics and as a herbal medicine in treatments for cough,boils,goiters,stomach ailments,and urinary diseases,and for reducing the incidence of tumors,ulcers,and headaches.Despite the fact that seaweeds are frequently used in the practice of human health,little is known about the role of seaweed in the context of inflammation.This study aimed to investigate the influence of Jeju endemic seaweed on a mouse macrophage cell line(RAW 264.7) under the stimulation of lipopoly...
Keywords:Nitric oxide  Interleukin-6 (IL-6)  Prostaglandin E2 (PGE2)  Seaweeds  Pro-inflammatory mediators
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