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Parkinson’s disease (PD) is a heterogenous disease caused by multifactorial etiology. PD is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra and the accumulation of Lewy bodies. In this study, two Drosophila PD models by exposing Drosophila to rotenone (sporadic PD models) are proposed, and the human α-synuclein A30P protein (family PD models) in Drosophila is expressed respectively. Both models recapitulated the main human PD symptoms including the loss of dopaminergic neurons... 相似文献
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俞淑 《青海师范大学学报(哲学社会科学版)》1988,(4)
《直斋书录解题》是南宋陈振孙(号直斋,浙江安吉人)编著的一部著名的目录学著作。全书分经、史、子、集四部五十三类,其中仅九类有小序;共著录南宋前的历代古籍51180卷,超过了南宋官修目录《中兴馆阁书目》的44486卷,不仅是目录学史上的划时代巨著,而且是研究宋代历史文化的重要资料。 该书继承了前代目录学著作的优良传统,且有所创新和发展。每书不只记载书名,而是对各书的卷帙、撰人及其学术渊源、版本源流均有论及。尤其在解题中,或记古书款式,或志版刻情况,或说 相似文献
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